Global health R&D at work in Ohio
Cincinnati Children’s Hospital Medical Center led early stage clinical trials of two Shigella vaccine candidates. Worldwide, Shigella causes more than 150 million cases of severe diarrhea and dysentery annually, including 500,000 cases in the United States, and kills more than 1 million people each year, most of whom are young children in low-income countries. Antibiotics are the standard treatment, but drug-resistant strains are emerging, and no vaccine is yet available.